Nicholas Busby was born about 1587 in Norwich, co. Norfolk, England. He emigrated on 8 Apr 1637 from Yarmouth, co. Norfolk, England. He took the oath of freeman in Mar 1638. He was a selectman in 1640/41 in Watertown, Middlesex Co., Massachusetts. In 1646, he moved from Watertown, Middlesex Co., Massachusetts  to Boston, Suffolk Co., Massachusetts where he was a constable in 1649. He signed a will on 25 Jul 1657. He died on 28 Aug 1657 in Boston, Suffolk Co., Massachusetts. His estate was probated on 10 Sep 1657. He was a weaver while in Watertown, Middlesex Co., Massachusetts. He was married to Bridget Cocke on 24 Jun 1605 in St. Mary Coslany, Norwich, co. Norfolk, England.

Bridget Cocke was born about 1584 in Norwich, co. Norfolk, England. She died before 3 Jul 1660 in Boston, Suffolk Co., Massachusetts. Children were:

i. Richard Busby was born in 1606 in Norwich, co. Norfolk, England.
ii. Thomas Busby was born about 1607 in Norwich, co. Norfolk, England.
iii. Anne Busby.
iv. Nicholas Busby was born in 1610 in Norwich, co. Norfolk, England. He died before 25 Jul 1657.
v. John Busby was born about 1612 in Norwich, co. Norfolk, England.
vi. Susan Busby was born about 1613 in Norwich, co. Norfolk, England. She died before 1637.
vii. Catherine Busby was born in 1615 in Norwich, co. Norfolk, England.
viii. John Busby was born about 1617 in Norwich, co. Norfolk, England.
ix. Abraham Busby was born in 1618 in Norwich, co. Norfolk, England. He died on 20 Mar 1687.
x. Sarah Busby was born in 1619 in Norwich, co. Norfolk, England. She died on 25 Apr 1669 in Sudbury, Middlesex Co., Massachusetts.
xi. Amie Busby was born in 1622 in Norwich, co. Norfolk, England.
xii. Livewell Busby was born about 1628 in Norwich, co. Norfolk, England.