William Nickerson was born on 16 Oct 1604 in Norwich, co. Norfolk, England. He emigrated on 8 Apr 1637 from Yarmouth, co. Norfolk, England. They arrived on the "Rose". He took the oath of freeman on 2 May 1638. He took the oath of fidelity on 1 Jun 1641. He died between 30 Aug 1689 and 8 Sep 1690 in Chatham, Barnstable Co., Massachusetts. He was a weaver. He was married to Anne Busby about 1627 in Norwich, co. Norfolk, England.

Anne Busby was born about 1609 in Norwich, co. Norfolk, England. She died after 18 May 1686 in Chatham, Barnstable Co., Massachusetts. Children were:

i. Elizabeth Nickerson.
ii. Nicholas Nickerson.
iii. Robert Nickerson was born in 1631 in England. He died before 5 Apr 1710 in Chatham, Barnstable Co., Massachusetts.
iv. Anne Nickerson was born in England. She died about 1681 in Chatham, Barnstable Co., Massachusetts.
v. Samuel Nickerson was born in 1638 in Watertown, Middlesex Co., Massachusetts. He died before 17 Aug 1719 in Harwich, Barnstable Co., Massachusetts.
vi. John Nickerson was born in 1640 in Yarmouth, Barnstable Co., Massachusetts. He died before 1728. He was married to Sarah Williams.
vii. Thomas Nickerson.
viii. Sarah Nickerson was born about 1644 in Yarmouth, Barnstable Co., Massachusetts. She died after 1715 in Yarmouth, Barnstable Co., Massachusetts.
ix. William Nickerson Jr. was born on 1 Jun 1646 in Yarmouth, Barnstable Co., Massachusetts. He was baptized on 1 Jun 1646 in Barnstable, Barnstable Co., Massachusetts. He died on 7 Apr 1719 in Chatham, Barnstable Co., Massachusetts. He was married to Mercy Williams about 1670.
x. Joseph Nickerson was born in Dec 1647 in Yarmouth, Barnstable Co., Massachusetts. He died about 1731 in Harwich, Barnstable Co., Massachusetts.