Isaac Small was born about 1695 in Kittery, York Co., Province of Maine, Massachusetts. He died on 30 Oct 1765 in Cape Elizabeth, Cumberland Co., Province of Maine, Massachusetts. He was a whaler. He was also known as Isaac Smalley. He was married to Elizabeth Barnaby on 28 Nov 1722 in Truro, Barnstable Co., Massachusetts.

Elizabeth Barnaby was born on 5 Dec 1701 in Plymouth, Plymouth Co., Massachusetts. She died on 16 May 1743 in Cape Elizabeth, York Co., Province of Maine, Massachusetts. Children were:

i. Elizabeth Small was born in Oct 1723.
ii. James Small was born on 17 Aug 1734 in Falmouth, York Co., Province of Maine, Massachusetts. He died on 9 Dec 1812 in North Limington, York Co., Province of Maine, Massachusetts.
iii. Ruth Small.
iv. Isaac Small was born on 17 Aug 1740.